sST2 in the Literature: A Starting Reading List

A short reading list for groups entering sST2 work — and why we publish a reading list rather than a citation count.

Why a reading list, not a citation count

Several suppliers display the number of papers citing their own catalogue numbers. That is a genuine signal — but it is their number, built over decades, and we have no honest claim to it. What we can usefully offer is the literature on the analyte itself, so a new group can get oriented quickly.

Foundational biology

Weinberg et al., Circulation 2002 — expression and regulation of ST2 in cardiomyocytes and myocardial infarction. Sanada et al., Journal of Clinical Investigation 2007 — IL-33 and ST2 as a biomechanically induced, cardioprotective signalling system. Together these established why the soluble receptor is worth measuring at all.

Clinical and consensus literature

Januzzi et al., Journal of the American College of Cardiology 2007 — measurement of the interleukin family member ST2 in patients with acute dyspnoea. Pascual-Figal and Januzzi, American Journal of Cardiology 2015 — the biology of ST2, from the International ST2 Consensus Panel. If you are setting up an sST2 assay for the first time, start with the consensus paper.

How to use this list

These references concern the analyte and its biology, not our materials — we cite them to save you a literature search, and you should verify details against the original publications — searching the title in PubMed is the fastest route. We give author, journal and year rather than publisher links, because publisher URLs change and a dead link is worse than no link. If you are deciding between measuring soluble ST2 and a natriuretic peptide, the consensus paper and our comparison article answer that from different directions.

Ask a technical question